Alter Ego: Toto
First Appearance: Superman (vol. 1) #127 (Feb. 1959): "Titano the Super-Ape!"
First Appearance (Additional Details): (modern) Superman Annual (vol. 2) #1 (July 1987): "Tears for Titano!"
Super? (Has Super Powers/Special Abilities/Technology): Yes
Number of Appearances: 48
Ally: Lois Lane
Note: chimpanzee made gigantic; based on King Kong
Titano's intelligence was enhanced to the extent that he was considered one of the most intelligent animals in the world. His main enhancement, however, was his tremendous size. He apparently never achieved human-level intelligence.
It may be debatable whether Titano should best be classified as an "uplifted animal" or a "mutated animal." However he is classified, it is clear that he started out as a normal, un-mutated chimpanzee. He was exceptionally intelligent, but not super-intelligent or intelligent beyond the level that mainline chimpanzees can be. Thus, the question of "religious affiliation" is largely "not applicable" for Titano.
Even if Titano's intelligence was enhanced considerably by his mutation, he certainly never was part of any organized religious culture such as is exhibited by some groups of uplifted animals.
Suggested links for further research about this character and the character's religious affiliation: