Alter Ego: Ophelia Sarkissian
Other Names: Viper II; Madame Hydra; Madame Viper; White Princess; "Leona Hiss"; "Merriem Drew"; Mrs. Smith
First Appearance: (as Madame Hydra) Captain America (vol. 1) #110 (Feb. 1969): "No Longer Alone!"; (as Viper) Captain America (vol. 1) #180 (Dec. 1974): "The Coming of the Nomad!"
Super? (Has Super Powers/Special Abilities/Technology): Yes
Number of Appearances: 153
Comic Book Appearances: 152
TV, Film Appearances: 1
Ally: Silver Samurai
Employer: Red Skull
Note: former servant of Chthon
Tony Stark (Iron Man Annual #1, 2007, page 3): "Other aliases [for Madame Hydra] include The Viper, Leona Hiss, Merriem Drew, and Ophelia Sarkissian, which just might be her real name."
A second incarnation of the Serpent Squad appeared in Captain America #s 180-182, comprised of Viper (Dixon), the Eel, Princess Python, Cobra and Krang. The group tried to use the Serpent Crown to take over the world. In Captain America #180, the original Viper (Jordan Dixon) was replaced by a savage new up-and-comer of a super-villain: Madame Hydra. She fought and killed Viper so she could become the new "Viper," and she assumed his place in the Serpent Squad. Viper also battled Cobra and defeated him (but did not kill him) so that she could take his place as leader of the Serpent Squad.
In Captain America (vol. 1) #419, Viper utilized super-villain team she organized called Fangs. They were essentially pawns in her latest nihilist scheme. The team consisted of Bludgeon, Heatray, Razorblade, and Slither).
Suggested links for further research about this character and the character's religious affiliation: